T-Box 6 antibody (AA 241-330)

Catalog No. ABIN1714574

The Rabbit Polyclonal anti-T-Box 6 antibody has been validated for ELISA, IHC (p), ICC, IF (cc), IF (p) and IHC (fro). It is suitable to detect T-Box 6 in samples from Rat.

Quick Overview for T-Box 6 antibody (AA 241-330) (ABIN1714574)

Target: T-Box 6 (TBX6)

Reactivity: Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This T-Box 6 antibody is un-conjugated

Application: ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Product Details anti-T-Box 6 Antibody

Binding Specificity: AA 241-330

Cross-Reactivity: Rat

Predicted Reactivity: Human,Mouse,Dog,Cow,Horse,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human TBX6

Isotype: IgG

Application Details

Application Notes: ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

Target Details for T-Box 6

Target: T-Box 6 (TBX6)

Alternative Name: TBX6

Background:

Synonyms: SCDO5, T-box transcription factor TBX6, T-box protein 6, TBX6

Background: T-box transcription factor that plays an essential role in the determination of the fate of axial stem cells: neural vs mesodermal. Acts in part by down-regulating, a specific enhancer (N1) of SOX2, to inhibit neural development. Seems to play also an essential role in left/right axis determination and acts through effects on Notch signaling around the node as well as through an effect on the morphology and motility of the nodal cilia (By similarity).

Gene ID: 6911

UniProt: O95947